Publications

Foundational research and clinical insights shaping Restorative Reproductive Medicine

Get the Oestradiol Pregnancy Curve (Clinical Reference PDF)

A clear, week-by-week reference for serum oestradiol levels in pregnancy, including suggested treatment thresholds in pmol/L and pg/ml. Developed from published clinical research.

Restoration of serum estradiol and reduced incidence of miscarriage in patients with low serum estradiol during pregnancy: a retrospective cohort study using a multifactorial protocol including DHEA

Low serum estradiol in early pregnancy is associated with an elevated risk of miscarriage. We sought to determine whether efforts to restore low blood estradiol via estradiol or dehydroepiandrosterone (DHEA) supplementation would reduce the risk of miscarriage as part of a multifactorial symptom-based treatment protocol.

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Restorative reproductive medicine (RRM) outcomes compared to in-vitro fertilization (IVF) for the treatment of infertility: a retrospective evaluation of a 2019 clinic cohort compared to one cycle of IVF

A retrospective clinic-based analysis and referenced against publicly available data from IVF registries, as published by the Centers for Disease Control and Prevention (CDC) or the Society for Assisted Reproductive Technology (SART) in the USA, and the Human Fertilization and Embryology Authority (HFEA), in the UK. 

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Healthy Singleton Pregnancies from Restorative Reproductive Medicine After Failed IVF

Several authors have reported a variety of hormonal profiles in normally fertile women. Moreover, a continuum from normal to abnormal cycles exists (1–6). Some ovulation disorders may represent minor deviations from the regular ovulatory process. We evaluated whether factors associated with luteal phase deficiency are also predictors of various minor luteal phase deficiencies in normally cycling women.

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Hormonal Predictors of Abnormal Luteal Phases in Normally Cycling Women

Explore potential relationships between preovulatory, periovulatory, and luteal-phase characteristics in normally cycling women.

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Progesterone in Women with Recurrent Miscarriages

In summarizing their well-executed randomized trial, Progesterone in Recurrent Miscarriages (PROMISE), Coomarasamy et al. (Nov. 26 issue)1 state that there is no evidence of benefit from progesterone supplementation “in the first trimester” of pregnancy among women who have had three or more miscarriages.

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NaProTechnology (Natural Procreative Technology) - A Multifactorial Approach to the Chronic Problem of Infertility

Infertility is usually a consequence of multiple chronic conditions rather than a single acute condition. We propose that it is erroneous to apply acute medical interventions to a condition that is chronic in nature.

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Outcomes from Treatment of Infertility with Natural Procreative Technology in an Irish General Practice

We evaluated outcomes in couples treated for infertility with natural procreative technology (NaProTechnology, NPT), a systematic medical approach for optimizing physiologic conditions for conception in vivo, from an Irish general practice.

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